Alterations in the GyrA Subunit of DNA Gyrase and the ParC Subunit of DNA Topoisomerase IV Associated with Quinolone Resistance in Enterococcus faecalis

The gyrA and parC genes of 31 clinical isolates of Enterococcus faecalis, including fluoroquinolone-resistant isolates, were partially sequenced and analyzed for target alterations. Topoisomerase IV may be a primary target in E. faecalis, but high-level fluoroquinolone resistance was associated with...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Kanematsu, Emiko, Deguchi, Takashi, Yasuda, Mitsuru, Kawamura, Takeshi, Nishino, Yoshinori, Kawada, Yukimichi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9527801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.2.433
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