Alterations in the GyrA Subunit of DNA Gyrase and the ParC Subunit of DNA Topoisomerase IV Associated with Quinolone Resistance in Enterococcus faecalis

The gyrA and parC genes of 31 clinical isolates of Enterococcus faecalis, including fluoroquinolone-resistant isolates, were partially sequenced and analyzed for target alterations. Topoisomerase IV may be a primary target in E. faecalis, but high-level fluoroquinolone resistance was associated with...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Kanematsu, Emiko, Deguchi, Takashi, Yasuda, Mitsuru, Kawamura, Takeshi, Nishino, Yoshinori, Kawada, Yukimichi
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1998
Fag:	Mechanisms of Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9527801/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.2.433
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