Toxicological Profile and Pharmacokinetics of a Unilamellar Liposomal Vesicle Formulation of Amphotericin B in Rats

AmBisome (ABLP) is a unilamellar liposomal preparation of amphotericin B that has demonstrated an improved safety profile compared to conventional amphotericin B. Single- and multiple-dose pharmacokinetics were determined by using noncompartmental methods for rats administered ABLP at 1, 3, 9, and 2...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Boswell, Garry W., Bekersky, Ihor, Buell, Donald, Hiles, Richard, Walsh, Thomas J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9527770/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.2.263
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