Antisense delivery using protamine–oligonucleotide particles
Protamine, a polycationic peptide (mol. wt 4000–4500), was evaluated as a potential penetration enhancer for phosphodiester antisense oligonucleotides (ODNs). Unique complexes in the form of nanoparticles were spontaneously formed, which we call ‘proticles’. The stability of the particles and the OD...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105384/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10773093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.10.e45 |
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