Antisense delivery using protamine–oligonucleotide particles

Protamine, a polycationic peptide (mol. wt 4000–4500), was evaluated as a potential penetration enhancer for phosphodiester antisense oligonucleotides (ODNs). Unique complexes in the form of nanoparticles were spontaneously formed, which we call ‘proticles’. The stability of the particles and the OD...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	Junghans, Monika, Kreuter, Jörg, Zimmer, Andreas
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 2000
Matèries:	NAR Methods Online
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105384/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10773093/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.10.e45
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