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Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA

The translational initiator codon in thymidylate synthetase (TS) mRNA is located in a stem–loop structure with a CC bubble. TS is an important target for anticancer drugs. Aminoglycoside antibiotics have been shown to specifically bind to TS mRNA site 1 constructs and, furthermore, specific binding...

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Bibliográfalaš dieđut
Publikašuvnnas:Nucleic Acids Res
Váldodahkkit: Cho, Junhyeong, Rando, Robert R.
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Oxford University Press 2000
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105371/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10773086/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.10.2158
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