Specific binding of Hoechst 33258 to site 1 thymidylate synthase mRNA
The translational initiator codon in thymidylate synthetase (TS) mRNA is located in a stem–loop structure with a CC bubble. TS is an important target for anticancer drugs. Aminoglycoside antibiotics have been shown to specifically bind to TS mRNA site 1 constructs and, furthermore, specific binding...
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| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105371/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10773086/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.10.2158 |
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