Group D Adenoviruses Infect Primary Central Nervous System Cells More Efficiently than Those from Group C

Group C adenovirus-mediated gene transfer to central nervous system cells is inefficient. We found that wild-type group D viruses, or recombinant adenovirus type 2 (Ad2) (group C) modified to contain Ad17 (group D) fiber, were more efficient in infecting primary cultures of neurons. Together with st...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Chillon, Miguel, Bosch, Assumpció, Zabner, Joseph, Law, Lane, Armentano, Donna, Welsh, Michael J., Davidson, Beverly L.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1999
Materias:	Gene Therapy
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104501/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971839/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.2537-2540.1999
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