Mutant Influenza Viruses with a Defective NS1 Protein Cannot Block the Activation of PKR in Infected Cells

A short model genome RNA and also the genome RNA of influenza A virus bearing both 5′- and 3′-terminal common sequences activated the interferon-induced double-stranded-RNA-dependent protein kinase, PKR, by stimulating autophosphorylation in vitro. The activated PKR catalyzed phosphorylation of the...

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Pubblicato in:	J Virol
Autori principali:	Hatada, Eriko, Saito, Sakura, Fukuda, Ryuji
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104489/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971827/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.2425-2433.1999
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