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A Hairpin Loop at the 5′ End of Influenza A Virus Virion RNA Is Required for Synthesis of Poly(A)(+) mRNA In Vitro

We present evidence, based on extensive mutagenesis, that a hairpin loop at the 5′ end of influenza A virus virion RNA (vRNA) is required for the synthesis of polyadenylated mRNA from model vRNA templates in vitro. The hairpin loop, which we term the vRNA 5′ hook, contains a stem of 2 bp formed by t...

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Bibliographische Detailangaben
Hauptverfasser: Pritlove, David C., Poon, Leo L. M., Devenish, Louise J., Leahy, Mike B., Brownlee, George G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC104455/
https://ncbi.nlm.nih.gov/pubmed/9971793
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