A Hairpin Loop at the 5′ End of Influenza A Virus Virion RNA Is Required for Synthesis of Poly(A)(+) mRNA In Vitro

We present evidence, based on extensive mutagenesis, that a hairpin loop at the 5′ end of influenza A virus virion RNA (vRNA) is required for the synthesis of polyadenylated mRNA from model vRNA templates in vitro. The hairpin loop, which we term the vRNA 5′ hook, contains a stem of 2 bp formed by t...

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Vydáno v:	J Virol
Hlavní autoři:	Pritlove, David C., Poon, Leo L. M., Devenish, Louise J., Leahy, Mike B., Brownlee, George G.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1999
Témata:	Replication
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9971793/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.3.2109-2114.1999
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