Factors Governing the Activity In Vivo of Ribozymes Transcribed by RNA Polymerase III

In order to determine the parameters that govern the activity of a ribozyme in vivo, we made a systematic analysis of chimeric tRNA(Val) ribozymes by measuring their cleavage activities in vitro as well as the steady-state levels of transcripts, the half-lives of transcribed tRNA(Val) ribozymes, and...

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Hlavní autoři: Koseki, Shiori, Tanabe, Tsuyoshi, Tani, Kenzaburo, Asano, Shigetaka, Shioda, Tatsuo, Nagai, Yoshiyuki, Shimada, Takashi, Ohkawa, Jun, Taira, Kazunari
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC104427/
https://ncbi.nlm.nih.gov/pubmed/9971765
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