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Factors Governing the Activity In Vivo of Ribozymes Transcribed by RNA Polymerase III
In order to determine the parameters that govern the activity of a ribozyme in vivo, we made a systematic analysis of chimeric tRNA(Val) ribozymes by measuring their cleavage activities in vitro as well as the steady-state levels of transcripts, the half-lives of transcribed tRNA(Val) ribozymes, and...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
1999
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC104427/ https://ncbi.nlm.nih.gov/pubmed/9971765 |
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