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DNA Hairpin Opening Mediated by the RAG1 and RAG2 Proteins
The lymphoid cell-specific proteins RAG1 and RAG2 initiate V(D)J recombination by cleaving DNA adjacent to recombination signals, generating blunt signal ends and covalently sealed, hairpin coding ends. A critical next step in the reaction is opening of the hairpins, but the factor(s) responsible ha...
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Autores principales: | , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
American Society for Microbiology
1999
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC104375/ https://ncbi.nlm.nih.gov/pubmed/10330156 |
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