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DNA Hairpin Opening Mediated by the RAG1 and RAG2 Proteins

The lymphoid cell-specific proteins RAG1 and RAG2 initiate V(D)J recombination by cleaving DNA adjacent to recombination signals, generating blunt signal ends and covalently sealed, hairpin coding ends. A critical next step in the reaction is opening of the hairpins, but the factor(s) responsible ha...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Shockett, Penny E., Schatz, David G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104375/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10330156/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.6.4159
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