Improved Production of Gutted Adenovirus in Cells Expressing Adenovirus Preterminal Protein and DNA Polymerase
Production of gutted, or helper-dependent, adenovirus vectors by current methods is inefficient. Typically, a plasmid form of the gutted genome is transfected with helper viral DNA into 293 cells; the resulting lysate is serially passaged to increase the titer of gutted virions. Inefficient producti...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | J Virol |
|---|---|
| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Microbiology (ASM)
1999
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438876/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7835-7841.1999 |
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