Targeted Recombination Demonstrates that the Spike Gene of Transmissible Gastroenteritis Coronavirus Is a Determinant of Its Enteric Tropism and Virulence

Targeted recombination within the S (spike) gene of transmissible gastroenteritis coronavirus (TGEV) was promoted by passage of helper respiratory virus isolates in cells transfected with a TGEV-derived defective minigenome carrying the S gene from an enteric isolate. The minigenome was efficiently...

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Xehetasun bibliografikoak

Argitaratua izan da:	J Virol
Egile Nagusiak:	Sánchez, Carlos M., Izeta, Ander, Sánchez-Morgado, Jose M., Alonso, Sara, Sola, Isabel, Balasch, Mónica, Plana-Durán, Juan, Enjuanes, Luis
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1999
Gaiak:	Pathogenesis and Immunity
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104288/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10438851/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.9.7607-7618.1999
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