Effective Induction of Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes in Macaques by Using a Multiepitope Gene and DNA Prime-Modified Vaccinia Virus Ankara Boost Vaccination Regimen

DNA and modified vaccinia virus Ankara (MVA) are vaccine vehicles suitable and safe for use in humans. Here, by using a multicytotoxic T-lymphocyte (CTL) epitope gene and a DNA prime-MVA boost vaccination regimen, high levels of CTLs specific for a single simian immunodeficiency virus (SIV) gag-deri...

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Detalhes bibliográficos
Main Authors: Hanke, Tomas, Samuel, Rachel V., Blanchard, Tom J., Neumann, Veronica C., Allen, Todd M., Boyson, Jon E., Sharpe, Sally A., Cook, Nicola, Smith, Geoffrey L., Watkins, David I., Cranage, Martin P., McMichael, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC104279/
https://ncbi.nlm.nih.gov/pubmed/10438842
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