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Subdomain Folding and Biological Activity of the Core Structure from Human Immunodeficiency Virus Type 1 gp41: Implications for Viral Membrane Fusion

The envelope glycoprotein of human immunodeficiency virus type 1 (HIV-1) consists of two subunits, gp120 and gp41. The extraviral portion (ectodomain) of gp41 contains an α-helical domain that likely represents the core of the fusion-active conformation of the molecule. Here we report the identifica...

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Autori principali: Lu, Min, Ji, Hong, Shen, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC104224/
https://ncbi.nlm.nih.gov/pubmed/10196341
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