Recombinant Respiratory Syncytial Virus Bearing a Deletion of either the NS2 or SH Gene Is Attenuated in Chimpanzees

The NS2 and SH genes of respiratory syncytial virus (RSV) have been separately deleted from a recombinant wild-type RSV strain, A2 (M. N. Teng and P. L. Collins, J. Virol. 73:466–473, 1998; A. Bukreyev et al., J. Virol. 71:8973–8982, 1997; and this study). The resulting viruses, designated rA2ΔNS2 a...

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Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Whitehead, Stephen S., Bukreyev, Alexander, Teng, Michael N., Firestone, Cai-Yen, St. Claire, Marisa, Elkins, William R., Collins, Peter L., Murphy, Brian R.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1999
Assuntos:	Pathogenesis and Immunity
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104109/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074199/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.3438-3442.1999
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