The Retinoblastoma Protein Alters the Phosphorylation State of Polyomavirus Large T Antigen in Murine Cell Extracts and Inhibits Polyomavirus Origin DNA Replication

The retinoblastoma tumor suppressor protein (pRb) can associate with the transforming proteins of several DNA tumor viruses, including the large T antigen encoded by polyomavirus (Py T Ag). Although pRb function is critical for regulating progression from G(1) to S phase, a role for pRb in S phase h...

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Main Authors: Reynisdóttir, Inga, Bhattacharyya, Subarna, Zhang, Dong, Prives, Carol
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Virus-Cell Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC104060/
https://ncbi.nlm.nih.gov/pubmed/10074150
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