Genetic Evidence that EBNA-1 Is Needed for Efficient, Stable Latent Infection by Epstein-Barr Virus

Replication and maintenance of the 170-kb circular chromosome of Epstein-Barr virus (EBV) during latent infection are generally believed to depend upon a single viral gene product, the nuclear protein EBNA-1. EBNA-1 binds to two clusters of sites at oriP, an 1,800-bp sequence on the EBV genome which...

Full description

Saved in:
Bibliographic Details
Main Authors: Lee, May-Ann, Diamond, Margaret E., Yates, John L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC104057/
https://ncbi.nlm.nih.gov/pubmed/10074147
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items