Structure‐based design of antibodies targeting the EBNA1 DNA‐binding domain to block Epstein–Barr virus latent infection and tumor growth

Abstract The Epstein–Barr virus (EBV) nuclear antigen 1 (EBNA1) is critically involved in maintaining episomes during latent infection and promoting tumorigenesis. The development of an epitope‐specific monoclonal antibody (mAb) for EBNA1 holds great promise due to its high affinity and specificity,...

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Xehetasun bibliografikoak

Egile Nagusiak:	Yongyue Han, Fang Wu, Ying Zhang, Jun Liu, Yuzhe Wu, Yuecheng Wang, Xiwen Jiang, Xin Chen, Wei Xu
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Wiley 2024-10-01
Saila:	MedComm
Gaiak:	Epstein–Barr virus latent infection Epstein–Barr virus nuclear antigen 1 monoclonal antibody tumor
Sarrera elektronikoa:	https://doi.org/10.1002/mco2.739
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