Genetic Evidence that EBNA-1 Is Needed for Efficient, Stable Latent Infection by Epstein-Barr Virus

Replication and maintenance of the 170-kb circular chromosome of Epstein-Barr virus (EBV) during latent infection are generally believed to depend upon a single viral gene product, the nuclear protein EBNA-1. EBNA-1 binds to two clusters of sites at oriP, an 1,800-bp sequence on the EBV genome which...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Lee, May-Ann, Diamond, Margaret E., Yates, John L.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1999
Subjects:	Virus-Cell Interactions
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104057/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074147/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.2974-2982.1999
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