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Opposing Effects of Human Immunodeficiency Virus Type 1 Matrix Mutations Support a Myristyl Switch Model of Gag Membrane Targeting

Targeting of the human immunodeficiency virus type 1 (HIV-1) Gag precursor Pr55(gag) to the plasma membrane, the site of virus assembly, is primarily mediated by the N-terminal matrix (MA) domain. N-myristylation of MA is essential for the stable association of Pr55(gag) with membranes and for virus...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:J Virol
Ngā kaituhi matua: Paillart, Jean-Christophe, Göttlinger, Heinrich G.
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Microbiology (ASM) 1999
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC104015/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.4.2604-2612.1999
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