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NMR Structure of the Myristylated Feline Immunodeficiency Virus Matrix Protein

Membrane targeting by the Gag proteins of the human immunodeficiency viruses (HIV types-1 and -2) is mediated by Gag’s N-terminally myristylated matrix (MA) domain and is dependent on cellular phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2]. To determine if other lentiviruses employ a similar memb...

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Principais autores: Lola A. Brown, Cassiah Cox, Janae Baptiste, Holly Summers, Ryan Button, Kennedy Bahlow, Vaughn Spurrier, Jenna Kyser, Benjamin G. Luttge, Lillian Kuo, Eric O. Freed, Michael F. Summers
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2015-04-01
Series:Viruses
Assuntos:
Feline immunodeficiency virus (FIV)
nuclear magnetic resonance (NMR)
protein structure
retrovirus assembly
membrane targeting
phosphatidylinositol-4,5-bisphosphate [PI(4,5)-P2
PIP2]
Acceso en liña:http://www.mdpi.com/1999-4915/7/5/2210
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