T134, a Small-Molecule CXCR4 Inhibitor, Has No Cross-Drug Resistance with AMD3100, a CXCR4 Antagonist with a Different Structure

T22, an analog of polyphemusin II (18 amino acid residues), was found to block T-tropic human immunodeficiency virus type 1 (HIV-1) entry into target cells as a CXCR4 inhibitor. We synthesized T134, a small analog (14 amino acid residues) of T22 with reduced positive charges. T134 exhibited highly p...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Arakaki, Rieko, Tamamura, Hirokazu, Premanathan, Mariappan, Kanbara, Kenji, Ramanan, Sivasundaram, Mochizuki, Katsura, Baba, Masanori, Fujii, Nobutaka, Nakashima, Hideki
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 1999
נושאים:
Virus-Cell Interactions
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC104006/
https://ncbi.nlm.nih.gov/pubmed/9882387
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים