Perforin Is Essential for Control of Ectromelia Virus but Not Related Poxviruses in Mice
Lack of perforin renders the relatively resistant mouse strain C57BL/6 highly susceptible to the natural mouse pathogen ectromelia virus, a cytopathic orthopoxvirus. This is indicated by increased mortality, elevated virus titers and pathology in liver and spleen, and increased levels of liver enzym...
Kaydedildi:
| Yayımlandı: | J Virol |
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| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1999
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103996/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882377/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1665-1667.1999 |
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