Identification of Mutations Contributing to the Temperature-Sensitive, Cold-Adapted, and Attenuation Phenotypes of the Live-Attenuated Cold-Passage 45 (cp45) Human Parainfluenza Virus 3 Candidate Vaccine

The live-attenuated human parainfluenza virus 3 (PIV3) cold-passage 45 (cp45) candidate vaccine was shown previously to be safe, immunogenic, and phenotypically stable in seronegative human infants. Previous findings indicated that each of the three amino acid substitutions in the L polymerase prote...

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-д хэвлэсэн:	J Virol
Үндсэн зохиолчид:	Skiadopoulos, Mario H., Surman, Sonja, Tatem, Joanne M., Paschalis, Maribel, Wu, Shin-Lu, Udem, Stephen A., Durbin, Anna P., Collins, Peter L., Murphy, Brian R.
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology (ASM) 1999
Нөхцлүүд:	Vaccines and Antiviral Agents
Онлайн хандалт:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103961/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9882342/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.2.1374-1381.1999
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