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A sensitive scanning technology for low frequency nuclear point mutations in human genomic DNA

Knowledge of the kinds and numbers of nuclear point mutations in human tissues is essential to the understanding of the mutation mechanisms underlying genetic diseases. However, nuclear point mutant fractions in normal humans are so low that few methods exist to measure them. We have now developed a...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Li-Sucholeiki, Xiao-Cheng, Thilly, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103317/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10756211/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.9.e44
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