Načítá se...

Congenital thiopurine methyltransferase deficiency and 6-mercaptopurine toxicity during treatment for acute lymphoblastic leukaemia.

Two children with acute lymphoblastic leukaemia (ALL) taking daily 6-mercaptopurine as part of a national UK therapeutic trial repeatedly developed profound myelosuppression on 25% of the standard protocol dose. Both were found to have undetectable intracellular activity of thiopurine methyltransfer...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Lennard, L, Gibson, B E, Nicole, T, Lilleyman, J S
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1029622/
https://ncbi.nlm.nih.gov/pubmed/8257179
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!