Regulation of the RNA-dependent protein kinase by triple helix formation
The RNA-dependent protein kinase (PKR) is an interferon-induced, RNA-activated enzyme that phosphorylates the α-subunit of the translation initiation factor eIF-2, inhibiting its function. PKR is activated in vitro by binding to double-stranded RNA (dsRNA) molecules of ~30 bp or longer. Here we show...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102732/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10871369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.12.2369 |
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