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A novel functional genomics approach identifies mTERT as a suppressor of fibroblast transformation

As a tool for functional genomics, a hairpin ribozyme gene library with randomized target recognition sequences was constructed in a retroviral vector. This library has the potential to target and cleave any possible RNA substrate. Mouse fibroblasts transduced with this ribozyme gene vector library...

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Detalhes bibliográficos
Main Authors: Li, Qi-Xiang, Robbins, Joan M., Welch, Peter J., Wong-Staal, Flossie, Barber, Jack R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102704/
https://ncbi.nlm.nih.gov/pubmed/10871412
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