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The role of trans-acting factors and DNA-bending in the silencing of human β-globin gene expression
The molecular mechanisms which govern the developmental specificity of human β-globin gene transcription have been studied in K562 cells, a human eyrthroleukemia line that expresses minimal β-globin. Protein-binding analysis reveals that the 5′ region contains three elements bound by trans-acting f...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC102669/ https://ncbi.nlm.nih.gov/pubmed/10908341 |
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