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Activation of the Myc oncoprotein leads to increased turnover of thrombospondin-1 mRNA

The Myc oncoprotein is implicated in transcriptional regulation of a variety of genes pertaining to cell cycle and neoplastic transformation. Examples of both positive and negative regulation have been reported that involve E-box and initiator (Inr) promoter elements, respectively. In both cases, My...

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Main Authors: Janz, Annette, Sevignani, Cinzia, Kenyon, Karla, Ngo, Cam V., Thomas-Tikhonenko, Andrei
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2000
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC102633/
https://ncbi.nlm.nih.gov/pubmed/10871348
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