Improving dideoxynucleotide-triphosphate utilisation by the hyper-thermophilic DNA polymerase from the archaeon Pyrococcus furiosus

Polymerases from the Pol-I family which are able to efficiently use ddNTPs have demonstrated a much improved performance when used to sequence DNA. A number of mutations have been made to the gene coding for the Pol-II family DNA polymerase from the archaeon Pyrococcus furiosus with the aim of impro...

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Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Evans, Steven J., Fogg, Mark J., Mamone, Anthony, Davis, Maria, Pearl, Laurence H., Connolly, Bernard A.
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 2000
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666444/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.5.1059
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