Structures of m-iodo Hoechst–DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design

The DNA photosensitisers m-iodo Hoechst and m-iodo, p-methoxy Hoechst have been co-crystallised with the oligonucleotide d(CGCGAATTCGCG)(2) and their crystal structures determined. The crystals were then subjected to slow dehydration, which reduced their solvent contents from 40 (normal) to 30 (part...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Squire, Christopher J., Baker, L. J., Clark, George R., Martin, Roger F., White, Jonathan
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2000
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102593/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.5.1252
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!