Structures of m-iodo Hoechst–DNA complexes in crystals with reduced solvent content: implications for minor groove binder drug design

The DNA photosensitisers m-iodo Hoechst and m-iodo, p-methoxy Hoechst have been co-crystallised with the oligonucleotide d(CGCGAATTCGCG)(2) and their crystal structures determined. The crystals were then subjected to slow dehydration, which reduced their solvent contents from 40 (normal) to 30 (part...

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書誌詳細

出版年:	Nucleic Acids Res
主要な著者:	Squire, Christopher J., Baker, L. J., Clark, George R., Martin, Roger F., White, Jonathan
フォーマット:	Artigo
言語:	Inglês
出版事項:	Oxford University Press 2000
主題:	Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102593/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666470/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.5.1252
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