Interstrand cross-linking by Adriamycin in nuclear and mitochondrial DNA of MCF-7 cells
Activation of Adriamycin by formaldehyde leads to the formation of drug–DNA adducts in vitro and these adducts stabilise the DNA to such a degree that they function as virtual interstrand cross-links. The formation of these virtual interstrand cross-links by Adriamycin was investigated in MCF-7 cell...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102585/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10648796/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.4.1019 |
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