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p73 competes with p53 and attenuates its response in a human ovarian cancer cell line
The transcriptional activity of the p53 tumor suppressor protein is crucial for the regulation of cell growth, apoptosis and tumor progression. The first identified p53 relative, p73, was reported to be monoallelically expressed in normal tissues. In some tumors, loss of heterozygosity was associate...
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Main Authors: | , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Oxford University Press
2000
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC102516/ https://ncbi.nlm.nih.gov/pubmed/10606650 |
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