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Grx5 Is a Mitochondrial Glutaredoxin Required for the Activity of Iron/Sulfur Enzymes

Yeast cells contain a family of three monothiol glutaredoxins: Grx3, 4, and 5. Absence of Grx5 leads to constitutive oxidative damage, exacerbating that caused by external oxidants. Phenotypic defects associated with the absence of Grx5 are suppressed by overexpression of SSQ1 and ISA2, two genes in...

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Bibliografiske detaljer
Main Authors: Rodríguez-Manzaneque, María Teresa, Tamarit, Jordi, Bellí, Gemma, Ros, Joaquim, Herrero, Enrique
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC102255/
https://ncbi.nlm.nih.gov/pubmed/11950925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-10-0517
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