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Grx5 Is a Mitochondrial Glutaredoxin Required for the Activity of Iron/Sulfur Enzymes

Yeast cells contain a family of three monothiol glutaredoxins: Grx3, 4, and 5. Absence of Grx5 leads to constitutive oxidative damage, exacerbating that caused by external oxidants. Phenotypic defects associated with the absence of Grx5 are suppressed by overexpression of SSQ1 and ISA2, two genes in...

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Autores principales: Rodríguez-Manzaneque, María Teresa, Tamarit, Jordi, Bellí, Gemma, Ros, Joaquim, Herrero, Enrique
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC102255/
https://ncbi.nlm.nih.gov/pubmed/11950925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.01-10-0517
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