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DREAM-αCREM Interaction via Leucine-Charged Domains Derepresses Downstream Regulatory Element-Dependent Transcription

Protein kinase A-dependent derepression of the human prodynorphin gene is regulated by the differential occupancy of the Dyn downstream regulatory element (DRE) site. Here, we show that a direct protein-protein interaction between DREAM and the CREM repressor isoform, αCREM, prevents binding of DREA...

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Udgivet i:Mol Cell Biol
Principais autores: Ledo, Fran, Carrión, Angel M., Link, Wolfgang A., Mellström, Britt, Naranjo, José R.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102170/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11094064/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.24.9120-9126.2000
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