Template/Primer Requirements and Single Nucleotide Incorporation by Hepatitis C Virus Nonstructural Protein 5B Polymerase

Nonstructural protein 5B (NS5B) of hepatitis C virus (HCV) possesses an RNA-dependent RNA polymerase activity responsible for viral genome RNA replication. Despite several reports on the characterization of this essential viral enzyme, little is known about the reaction pathway of NS5B-catalyzed nuc...

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Pubblicato in:	J Virol
Autori principali:	Zhong, Weidong, Ferrari, Eric, Lesburg, Charles A., Maag, David, Ghosh, Saikat Kumar B., Cameron, Craig E., Lau, Johnson Y. N., Hong, Zhi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Replication
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102112/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982360/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.19.9134-9143.2000
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