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Wild-Type Herpes Simplex Virus 1 Blocks Programmed Cell Death and Release of Cytochrome c but Not the Translocation of Mitochondrial Apoptosis-Inducing Factor to the Nuclei of Human Embryonic Lung Fibroblasts

Programmed cell death activated by herpes simplex virus 1 mutants can be caspase dependent or independent depending on the nature of the infected cell. The recently discovered mitochondrial apoptosis-inducing factor (AIF) on activation is translocated to the nucleus and induces programmed cell death...

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Библиографические подробности
Опубликовано в::J Virol
Главные авторы: Zhou, Guoying, Roizman, Bernard
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2000
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102101/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982349/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.19.9048-9053.2000
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