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Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase α-primase

The wild-type form of p53 contains an intrinsic 3′–5′-exonuclease activity. As p53 forms a complex with DNA polymerase α-primase (pol-prim) in vivo this finding suggests that p53 might cooperate with pol-prim to stabilize the genetic information of living cells. To test this hypothesis, exonuclease-...

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書目詳細資料
發表在:Nucleic Acids Res
Principais autores: Melle, Christian, Nasheuer, Heinz-Peter
格式: Artigo
語言:Inglês
出版: Oxford University Press 2002
主題:
在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101832/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917009/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.7.1493
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