Physical and functional interactions of the tumor suppressor protein p53 and DNA polymerase α-primase
The wild-type form of p53 contains an intrinsic 3′–5′-exonuclease activity. As p53 forms a complex with DNA polymerase α-primase (pol-prim) in vivo this finding suggests that p53 might cooperate with pol-prim to stabilize the genetic information of living cells. To test this hypothesis, exonuclease-...
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| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101832/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11917009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/30.7.1493 |
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