Suppression of Macrophage Activation with CNI-1493 Increases Survival in Infant Rats with Systemic Haemophilus influenzae Infection

CNI-1493, a potent macrophage deactivator, was used to treat infant rats systemically infected with Haemophilus influenzae type b (Hib). CNI-1493 was injected 1 h prior to bacterial inoculation and 24 h later and resulted in a 75 percent increased rate of survival compared to that for untreated cont...

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Main Authors: Granert, Carl, Abdalla, Hana, Lindquist, Lars, Diab, Asim, Bahkiet, Moiz, Tracey, Kevin J., Andersson, Jan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Bacterial Infections
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC101796/
https://ncbi.nlm.nih.gov/pubmed/10948162
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