The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation

Metastatic Ewing Sarcoma carries a poor prognosis, and novel therapeutics to prevent and treat metastatic disease are greatly needed. Recent evidence demonstrates that tumor-associated macrophages in Ewing Sarcoma are associated with more advanced disease. While some macrophage phenotypes (M1) exhib...

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Pubblicato in:PLoS One
Autori principali: Hesketh, Anthony J., Maloney, Caroline, Behr, Christopher A., Edelman, Morris C., Glick, Richard D., Al-Abed, Yousef, Symons, Marc, Soffer, Samuel Z., Steinberg, Bettie M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692435/
https://ncbi.nlm.nih.gov/pubmed/26709919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145197
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