The Macrophage Inhibitor CNI-1493 Blocks Metastasis in a Mouse Model of Ewing Sarcoma through Inhibition of Extravasation

Metastatic Ewing Sarcoma carries a poor prognosis, and novel therapeutics to prevent and treat metastatic disease are greatly needed. Recent evidence demonstrates that tumor-associated macrophages in Ewing Sarcoma are associated with more advanced disease. While some macrophage phenotypes (M1) exhib...

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Publicado en:PLoS One
Autores principales: Hesketh, Anthony J., Maloney, Caroline, Behr, Christopher A., Edelman, Morris C., Glick, Richard D., Al-Abed, Yousef, Symons, Marc, Soffer, Samuel Z., Steinberg, Bettie M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692435/
https://ncbi.nlm.nih.gov/pubmed/26709919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145197
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