Pseudomonas aeruginosa Cell-to-Cell Signaling Is Required for Virulence in a Model of Acute Pulmonary Infection

Cell-to-cell signaling controls many virulence genes in Pseudomonas aeruginosa. We tested the virulence of las and rhl quorum-sensing mutants in neonatal mice. A lasI rhlI double mutant was nearly avirulent, and the respective single mutant strains were reduced in virulence compared with the wild-ty...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	Infect Immun
Hauptverfasser:	Pearson, James P., Feldman, Matthew, Iglewski, Barbara H., Prince, Alice
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2000
Schlagworte:	Bacterial Infections
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC101761/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10858254/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.68.7.4331-4334.2000
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!